先设置成丑的手写体
再运行下方随即调整行距的宏:

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Sub 字体修改()
' 字体修改 宏
Dim R_Character As Range

Dim FontSize(5)
' 字体大小在5个值之间进行波动,可以改写
FontSize(1) = "21"
FontSize(2) = "21.5"
FontSize(3) = "22"
FontSize(4) = "22.5"
FontSize(5) = "23"

Dim FontName(3)
'字体名称在三种字体之间进行波动,可改写,但需要保证系统拥有下列字体
FontName(1) = "陈静的字完整版"
FontName(2) = "萌妹子体"
FontName(3) = "李国夫手写体"

Dim ParagraphSpace(5)
'行间距 在一定以下值中均等分布,可改写
ParagraphSpace(1) = "12"
ParagraphSpace(2) = "13"
ParagraphSpace(3) = "20"
ParagraphSpace(4) = "7"
ParagraphSpace(5) = "12"

'不懂原理的话,不建议修改下列代码
For Each R_Character In ActiveDocument.Characters
VBA.Randomize
R_Character.Font.Name = FontName(Int(VBA.Rnd * 3) + 1)
R_Character.Font.Size = FontSize(Int(VBA.Rnd * 5) + 1)
R_Character.Font.Position = Int(VBA.Rnd * 3) + 1
R_Character.Font.Spacing = 0
Next

Application.ScreenUpdating = True

For Each Cur_Paragraph In ActiveDocument.Paragraphs
Cur_Paragraph.LineSpacing = ParagraphSpace(Int(VBA.Rnd * 5) + 1)
Next
Application.ScreenUpdating = True

End Sub